New Paper - B22 Kato
01.03.2024
New publication from Hiroki Kato's group
They have found that constitutive MDA5 signaling, and ADAR1 deficiency causing aberrant downstream activation of innate immune sensors MDA5 and PKR, disturb Treg homeostasis in mice, resulting in severe autoimmunity and lethality.
https://www.science.org/doi/10.1126/sciadv.adk0820
