A11 - Role of UNC93B1 in nucleic acid-sensing TLR function - relevance for the pathogenesis of systemic lupus erythematosus
This project will elucidate the molecular mechanisms underlying a novel monogenic form of early-onset SLE due to an UNC93B1 gain-of-function. By combining their expertise in pediatric immunology, innate immunity, and systems medicine, the investigators aim at translating basic research findings into novel therapeutic concepts targeting individual innate immune pathways, thus, accelerating precision medicine in autoimmune diseases.
Prof. Dr. Eicke LatzUniversity Hospital, Institute of Innate Immunity, University of Bonn +49 (0)228 287-51239 External web links: |
Prof. Dr. Min Ae Lee-Kirsch Speaker for Dresden External web links: |
